Robert De Niro to star in gangster drama ‘Wise Guys’ at Warner Bros.

Robert De Niro will share the screen with Hollywood legend Robert De Niro in the upcoming gangster drama “Wise Guys.”

The film, shot at Warner Bros. and destined to be played in theaters, will be directed by Barry Levinson, the veteran filmmaker who is best known for “Rain Man” and “Wag the Dog.” It reunites De Niro and Levinson, who previously teamed up on “Wag the Dog,” “Sleeper,” the HBO series “The Wizard of Lies,” and “What Just Happened.”

“Wise Guys” follows Italian-American crime bosses Vito Genovese and Frank Costello, who led their respective families through the 20th century. In 1957, Genovese attempted (and failed) to assassinate Costello, who was eventually injured and attempted to retire from the Mafia. De Niro should play the two main characters.

Nicholas Pileggi, the co-writer of Martin Scorsese’s crime epic “Goodfellas,” which starred De Niro, is writing the screenplay for “Wise Guys.” (“Goodfellas” is based on Pileggi’s 1985 book “Wiseguy: Life in a Mafia Family,” though it has no relation to Levinson’s film.)

For De Niro, “Wise Guys” is a throwback to the genre that made him a star. With ‘Goodfellas’, the actor made a name for himself in crime dramas like ‘The Godfather Part II’, ‘Mean Streets’ and ‘Casino’. His most recent credits include Scorsese’s “Joker” and “The Irishman,” which used extensive digital technology to age De Niro and his co-stars Al Pacino and Joe Pesci. He teams up with Scorsese again on Apple’s “Killers of the Flower Moon,” a Western crime drama about the 1920 Oklahoma murders in the Osage Nation.

Irwin Winkler, producer of “Rocky” and “Goodfellas”, will produce “Wise Guys”.

The Hollywood Reporter was first to report the news.